Our Platform
Understanding The Industry
Challenge and Opportunities
in Genetics
The biopharma industry is faced with high rates of clinical failure in innovative therapeutics, often due to a lack of high-confidence targets. Meanwhile, disease genetics data and data on how genetics impact gene/protein’s function are emerging in large scale and ready for translation. Furthermore, methodologies such as Mendelian Randomization are maturing, presenting promising paths for progress.
Our Platform
Translating Genetic Associations
into High-Confidence
Therapeutic Targets
At D2M, we leverage Genome Wide Association Studies (GWAS) along with emerging multi-functional omics data, gaining insights into novel therapeutic targets. Furthermore, we employ systemic Mendelian Randomization mimicking traditional randomized controlled trials for causal biology learning.
Our Platform
Broadened Immunotherapy
on Genetically Validated Pathway
Driven by the insights from genetics research, D2M is developing a broadened innovative immunotherapy for a variety of diseases including cancer, autoimmune disorders, and inflammation. We are committed to improving people’s health by addressing the root causes of disease.
Our Therapeutics Discovery Engine
Starting from targets identified from INGENUITI, we have established an integrated platform for target validation and antibody discovery, including both in vitro, in vivo functional assays. This platform enables us to screen and select for the best functional therapeutic antibodies by leveraging a diverse array of primary immune cells, established cell lines, and in vivo animal disease models.
It All Begins and Ends With Patients
Putting People First
Our research begins with the identification of disease gene in patients and concludes with innovative therapies for patients. Our decisions are driven primarily by patient’s unmet needs and science from human biology.
Building a Pipeline
We are using our INGENUITI platform to build a broadened immune therapy pipeline for cancer, autoimmune, and inflammation diseases.